Author

Rachel Offenbacher

Albert Einstein College of MedicineORCID 0000-0002-5211-6457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

David Mark LoebiD· 3 shared Da PengiD· 2 shared Patrick CahaniD· 2 shared Paul CieroiD· 2 shared Yuqi TaniD· 2 shared Adit L. TaliD· 1 shared Alexander FerrenaiD· 1 shared Bang H. HoangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

David Mark LoebORCID

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3 papers

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedMar 25, 2026

Comprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers Skp2 function in metastasis, genomic instability and immune activation and reveals additional target pathways

Alexander Ferrena, Ranxin Zhang, Jichuan Wang…·Bang H. Hoang

This study uses scRNA-seq to analyze murine osteosarcoma models and identifies Skp2's role in metastasis, genomic instability, and immune activation, revealing potential therapeutic targets.

2 citations

mousescRNA-seq

𝕏 PostBluesky

Cancer BiologyClinical Cancer ResearchPeer-reviewedJul 24, 2025

Polyamine Depletion by D, L-alpha-difluoromethylornithine Inhibits Ewing Sarcoma Metastasis by Inducing Ferroptosis

Rachel Offenbacher, Kyle W. Jackson, Masanori Hayashi…·David Mark Loeb

This study shows DFMO inhibits Ewing sarcoma metastasis by inducing ferroptosis through polyamine depletion.

13 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyMolecular Cancer TherapeuticsPeer-reviewedJan 9, 2025

Inhibition of DKK-1 by WAY262611 Inhibits Osteosarcoma Metastasis

Adit L. Tal, Shimara Gunawardana-Zeigler, Da Peng…·David Mark Loeb

This study shows that the small molecule inhibitor WAY262611 inhibits osteosarcoma metastasis by activating Wnt signaling and inducing osteoblastic differentiation.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky