Xinyu Yang

ARHGEF17 Deficiency Induces Endothelial Dysfunction and Intracranial Aneurysm Formation via RhoA/ROCK2/MLC Signaling Pathway

This study shows that ARHGEF17 deficiency causes endothelial dysfunction and intracranial aneurysms via the RhoA/ROCK2/MLC pathway, with ROCK inhibition reversing these effects.

Protein Language Model Predicts Mutation Pathogenicity and Clinical Prognosis

This study shows that pre-trained protein language models can predict mutation pathogenicity and patient survival in cancer, outperforming existing methods.