Author

Xinyu Yang

BGI Group (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Microbiology· 2 Bioinformatics· 1 Cancer Biology· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

Chuanyu LiuiD· 2 shared Haifeng ZhangiD· 2 shared Hewei LiangiD· 2 shared Liang Xiao· 2 shared Xin TongiD· 2 shared Yiyi Zhong· 2 shared Yuanqiang ZouiD· 2 shared Yuzheng Gu· 2 shared

Activity by Year

2022-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Chuanyu LiuORCID

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Author profile →

6 papers

Recent·Most cited

Venetoclax Resistance Creates Canonical Pyroptosis Vulnerability in AML

Qiuxia Wang, Shaohua Xu, Jizhen Cai, Qian Peng, Shuting Cao, Yanyan Zhang, Pengfei Lu, Xu Guo, Luzheng Liu, Wenna Fu, Song Shao, Jiazhuo Zhu, Bowen Qing, Hao Li, Kang Liu, , Ganqian Zhu

This study shows that venetoclax resistance in AML creates a vulnerability to canonical pyroptosis, which can be targeted with DPP8/9 inhibitors and NLRP3 activators.

bioRxiv · Oct 16, 2026 · PreprintCancer Biology

Comprehensive Complete-Genome Analysis of Lactobacillaceae and Bifidobacteriaceae Reveals Strain-Specific Metabolic Interactions in Chinese Gut Microbiota

Xin Tong, Hewei Liang, Yu Tian, Xinyu Yang, Ya Wang, Haoyu Wang, Yuzheng Gu, Zhihui Ma, Wenrui Su, Yanhong Liu, Sihang Cai, Zhiyin Lin, Peilin Zhang, Haifeng Zhang, Liang Xiao, , Yuanqiang Zou

The paper analyzes complete genomes of Lactobacillaceae and Bifidobacteriaceae strains to reveal strain-specific metabolic interactions in the Chinese gut microbiota.

bioRxiv · May 22, 2026 · PreprintMicrobiology

Dual-channel graph learning reveals similarity and complementarity in protein-protein interaction networks

Tao Tang, Taiguang Shen, Weizhuo Li, Yangyang Chen, Sisi Yuan, Yuansheng Liu, Xinyu Yang, Xiao Luo

DMG-PPI is a dual-channel graph neural network that models similarity and complementarity in PPI networks, improving prediction accuracy and providing interpretable insights into binding mechanisms.

PLoS Computational Biology · May 20, 2026Peer-reviewedBioinformatics

Complete Genomes of Cultivated Gut Bacteria Reveal Mobile Genetic Element-Driven Functional Diversity with Therapeutic Implications

Hao Wang, Yuzheng Gu, Wenxin He, Jinlong Yang, Hewei Liang, Mengmeng Wang, Zhinan Wu, Yangfeng Wen, Jinhong Wang, Xing Rao, Yaqi Fan, Jiayi Ma, Xinyu Yang, Xin Tong, Liye Yang, , Yuanqiang Zou

The paper presents a comprehensive compendium of fully circularized human gut bacterial genomes and reveals how mobile genetic elements drive functional diversity with therapeutic implications.

bioRxiv · Mar 25, 2026 · PreprintMicrobiology

Single-cell transcriptomic atlas of mouse oocyte development from growth to ovulation

Sining Zhou, Zhenshe Lin, Yiming Liu, Chang Liu, Xinyu Yang, Meichi Yue, Hong Wu, Rui Liu, Huinan Xu, Xiaoxi Zhou, Qian Liu, Zhe Zhang, Liyun Xiao, Jingxuan Zou, Jiamei Liu, , Chuanyu Liu

This study creates a single-cell transcriptomic atlas of mouse oocyte development from growth to ovulation using a new platform and integrates transcriptomic and morphological data to identify temporal shifts in gene expression.

bioRxiv · Mar 13, 2026 · PreprintDevelopmental Biology

Hypothalamic supramammillary neurons that project to the medial septum control wakefulness

Mengru Liang, Tingliang Jian, Wenjun Jin, Qianwei Chen, Xinyu Yang, Rui Wang, Jingyu Xiao, Zhiqi Yang, Xiang Liao, Xiaowei Chen, Liecheng Wang, Han Qin

The paper identifies hypothalamic supramammillary neurons projecting to the medial septum as a key circuit for controlling wakefulness through optogenetic and chemogenetic experiments.

bioRxiv · Dec 20, 2022 · PreprintNeuroscience