Author

Jonathan Monin

Hebrew University of JerusalemORCID 0000-0002-2196-6475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Osama HidmiiD· 3 shared Rami I. AqeilaniD· 3 shared Sara Oster Flayshman· 2 shared Diala Shatleh· 1 shared Jackelyn A. Alva-Ornelas· 1 shared Mark A. LaBargeiD· 1 shared Sara K. OsteriD· 1 shared Victoria L. SeewaldtiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Osama HidmiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Super-enhancers shape the landscape and repair dynamics of transcription-associated DNA breaks in cancer

Osama Hidmi, Diala Shatleh, Sara Oster Flayshman, Jonathan Monin, Rami I. Aqeilan

This study shows that super-enhancer activity influences transcription stress and DNA break repair dynamics in cancer, with γH2AX marking linked to DSB turnover and mutagenic vulnerability.

Science Advances · Jan 21, 2026Peer-reviewedMolecular Biology

The Breakome of BRCA1 and BRCA2 Pathway Mutation Carriers Reveals Early Processes in Breast Oncogenesis

Sara Oster Flayshman, Osama Hidmi, Jackelyn A. Alva-Ornelas, Jonathan Monin, Mark A. LaBarge, Victoria L. Seewaldt, Yotam Drier, Rami I. Aqeilan

This study identifies DSB patterns in BRCAmut carriers to reveal early oncogenic processes linked to HR deficiency.

Cell Death and Disease · Dec 5, 2025Peer-reviewedCancer Biology

R-loops and Topoisomerase 1 facilitate formation of transcriptional DSBs at gene bodies of hypertranscribed genes

Osama Hidmi, Sara K. Oster, Jonathan Monin, Rami I. Aqeilan

The paper investigates the role of R-loops and Topoisomerase 1 in forming transcriptional DSBs at hypertranscribed genes and links these breaks to cancer development.

bioRxiv · Dec 12, 2022 · PreprintMolecular Biology