Author
Hebrew University of JerusalemORCID 0000-0001-8674-7532Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Osama Hidmi, Diala Shatleh, Sara Oster Flayshman…·Rami I. Aqeilan
This study shows that super-enhancer activity influences transcription stress and DNA break repair dynamics in cancer, with γH2AX marking linked to DSB turnover and mutagenic vulnerability.
Sara Oster Flayshman, Osama Hidmi, Jackelyn A. Alva-Ornelas…·Rami I. Aqeilan
This study identifies DSB patterns in BRCAmut carriers to reveal early oncogenic processes linked to HR deficiency.
Daniel J. Steinberg, Asia Zonca, Dania Abdellatif…·Rami I. Aqeilan
This study identifies WWOX mutations' impact on neurogenesis and neuronal function in human organoids, showing gene therapy can restore function.
Osama Hidmi, Sara K. Oster, Jonathan Monin, Rami I. Aqeilan
The paper investigates the role of R-loops and Topoisomerase 1 in forming transcriptional DSBs at hypertranscribed genes and links these breaks to cancer development.