Carrie E. Leonard

Proteomic profiling of Elp1-deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

The paper uses proteomic profiling to identify molecular changes in Elp1-deficient trigeminal ganglia, revealing disruptions in neurotrophic and metabolic pathways in a familial dysautonomia mouse model.

N-cadherin facilitates trigeminal sensory neuron outgrowth and target tissue innervation

This study shows that N-cadherin is essential for trigeminal ganglion development, axon outgrowth, and target innervation by placodal and neural crest-derived neurons.

The transcriptional landscape of the developing chick trigeminal ganglion

This study uses RNA-sequencing to analyze chick trigeminal ganglion development, identifying key pathways in gangliogenesis and neuron maturation.

Loss of Elp1 disrupts trigeminal ganglion neurodevelopment in a model of Familial Dysautonomia

This study shows that loss of Elp1 in trigeminal ganglion neurons leads to impaired axon outgrowth, reduced target innervation, and decreased TrkA neuron survival, explaining facial pain and temperature sensation loss in Familial Dysautonomia.

EphA7 Isoforms Differentially Regulate Cortical Dendrite Development

This study identifies how two EphA7 isoforms differentially regulate cortical dendrite development through distinct signaling mechanisms.