Author

Sumaiyah Z. Shaha

University of AlbertaORCID 0000-0002-2235-4569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Meghan R. RiddelliD· 3 shared Wendy K. DuaniD· 3 shared Ivan K. DomingoiD· 2 shared Juan F. Garcia RivasiD· 2 shared Khushali PateliD· 2 shared Amy L. Brightwell· 1 shared Ashley ZubkowskiiD· 1 shared Bethan L. WilsoniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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3 shared papersDevelopmental Biology

Meghan R. RiddellORCID

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3 papers

Recent·Most cited

aPKC-ζ III promotes trophoblast fusion by altering Par-3 interactions with Hippo Signaling Kinase LATS1

Sumaiyah Z. Shaha, Wendy K. Duan, Juan F. Garcia Rivas, Ivan K. Domingo, Meghan R. Riddell

This study identifies aPKC-ζ III as a regulator of trophoblast fusion by modulating Hippo signaling through its interaction with Par-3 and LATS1.

Stem Cell Reports · Jun 25, 2026Peer-reviewedDevelopmental Biology

Placental cytotrophoblast microvillar stabilization is required for cell-cell fusion

Wendy K. Duan, Sumaiyah Z. Shaha, Juan F. Garcia Rivas, Bethan L. Wilson, Khushali Patel, Ivan K. Domingo, Meghan R. Riddell

The paper identifies microvillar stabilization via ezrin as essential for cytotrophoblast fusion and differentiation in the placenta.

Development · Apr 1, 2025Peer-reviewedDevelopmental Biology

Loss of polarity regulators initiates gasdermin E mediated pyroptosis in human maternal fetal interface trophoblasts

Khushali Patel, Jasmine Nguyen, Sumaiyah Z. Shaha, Amy L. Brightwell, Wendy K. Duan, Ashley Zubkowski, Meghan R. Riddell

The paper shows that loss of aPKC activity in trophoblasts leads to gasdermin E-mediated pyroptosis, linking polarity regulators to inflammation in the maternal-fetal interface.

bioRxiv · Jun 30, 2022 · PreprintDevelopmental Biology