Wendy K. Duan

This study shows that advanced maternal age impairs decidual angiogenesis and spiral artery remodeling in mice, contributing to pregnancy complications and cardiovascular risk.

This study identifies aPKC-ζ III as a regulator of trophoblast fusion by modulating Hippo signaling through its interaction with Par-3 and LATS1.

The paper identifies microvillar stabilization via ezrin as essential for cytotrophoblast fusion and differentiation in the placenta.

The paper shows that loss of aPKC activity in trophoblasts leads to gasdermin E-mediated pyroptosis, linking polarity regulators to inflammation in the maternal-fetal interface.