Developmental BiologybioRxivPreprint
Loss of polarity regulators initiates gasdermin E mediated pyroptosis in human maternal fetal interface trophoblasts
Khushali Patel, Jasmine Nguyen, Sumaiyah Z. Shaha…·Meghan R. Riddell
The paper shows that loss of aPKC activity in trophoblasts leads to gasdermin E-mediated pyroptosis, linking polarity regulators to inflammation in the maternal-fetal interface.
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