Pananghat Gayathri

Lateral interactions override nucleotide state in determining FtsZ filament curvature

This study shows that lateral interactions between FtsZ protofilaments override nucleotide state in determining filament curvature, with implications for Z-ring assembly and constriction.

Mutational analysis of the F plasmid partitioning protein ParA reveals novel residues required for oligomerisation and plasmid maintenance

This study identifies mutations in ParA that disrupt polymerization and plasmid maintenance, highlighting the role of ParA oligomerization in plasmid partitioning.

Di-HAMP domains of a cytoplasmic chemoreceptor modulate nucleoid array formation and downstream signalling

This study identifies HAMP domains in FrzCD that modulate DNA binding and oligomerization, affecting bacterial social behavior and array plasticity.

Distinct filament morphology and membrane tethering features of the dual FtsZs in Odinarchaeota

This study compares two FtsZ isoforms in Odinarchaeota, revealing distinct filament structures and membrane tethering mechanisms, highlighting evolutionary diversity in the FtsZ-Tubulin superfamily.

RomX, a novel prokaryotic regulator, links the response receiver domain of RomR with GTP-bound MglA for establishing Myxococcus xanthus polarity

This study determines the crystal structure of RomX, a novel prokaryotic regulator, and shows it interacts with MglA-GTP and RomR-REC domains to regulate MglA localization in Myxococcus xanthus.