Author

Patrizio Di Micco

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-2242-6294Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1

Frequent Co-Authors

Bissan Al‐LazikaniiD· 2 shared Adam SharpiD· 1 shared Amanda SwainiD· 1 shared Ana FerreiraiD· 1 shared Andrew C.B. CatoiD· 1 shared Antje NeebiD· 1 shared Bora GüreliD· 1 shared Borja MateosiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Bissan Al‐LazikaniORCID

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2 papers

Recent·Most cited

Probabilistic graph-based model uncovers previously unseen druggable vulnerabilities in major solid cancers

Ying Zhu, Stephanie Schmidt, Li Zhao, Chunjie Jiang, Patrizio Di Micco, Costas Mitsopoulos, P. Andrew Futreal, Bissan Al‐Lazikani

This paper introduces a graph-based model to identify druggable vulnerabilities in solid cancers, finding 43 novel targets by leveraging cooperativity in molecular networks.

bioRxiv · Jun 4, 2024 · PreprintCancer Biology

Targeting the BAG-1 family of co-chaperones in lethal prostate cancer.

Antje Neeb, Ines Figueiredo, Denisa Bogdan, Laura Cato, Jutta Stober, Juan M. Jiménez‐Vacas, Victor Gourain, Irene I. Lee, Rebecca Seeger, Claudia Muhle‐Goll, Bora Gürel, Jonathan C. Welti, Daniel Nava Rodrigues, Jan Rekowski, Xintao Qiu, , Adam Sharp

This study investigates Thio-2's mechanism of action in inhibiting AR signaling in CRPC, showing it acts independently of BAG-1 isoforms and with potential AR NTD binding.

bioRxiv · Oct 17, 2022 · PreprintMolecular Biology