Author

Denisa Bogdan

Institute of Cancer ResearchORCID 0000-0002-3017-4832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam SharpiD· 2 shared Johann Sebastian De BonoiD· 2 shared Wei YuaniD· 2 shared Amanda SwainiD· 1 shared Ana FerreiraiD· 1 shared Andrew C.B. CatoiD· 1 shared Antje NeebiD· 1 shared Ayesha A. ShafiiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Adam SharpORCID

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2 papers

Recent·Most cited

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer

Sumaira Sardar, Christopher M. McNair, Lakshmi Ravindranath, Saswati N. Chand, Wei Yuan, Denisa Bogdan, Jon C. Welti, Adam Sharp, Natalie K. Ryan, Liam A Knudsen, Matthew Joseph Schiewer, Elise G. DeArment, Thomas Janas, Xiaofeng A. Su, Lisa M. Butler, , Ayesha A. Shafi

This study identifies CBP/p300 as critical for DNA repair in prostate cancer and shows that targeting it enhances therapeutic response.

Oncogene · Sep 12, 2024Peer-reviewedCancer Biology

Targeting the BAG-1 family of co-chaperones in lethal prostate cancer.

Antje Neeb, Ines Figueiredo, Denisa Bogdan, Laura Cato, Jutta Stober, Juan M. Jiménez‐Vacas, Victor Gourain, Irene I. Lee, Rebecca Seeger, Claudia Muhle‐Goll, Bora Gürel, Jonathan C. Welti, Daniel Nava Rodrigues, Jan Rekowski, Xintao Qiu, , Adam Sharp

This study investigates Thio-2's mechanism of action in inhibiting AR signaling in CRPC, showing it acts independently of BAG-1 isoforms and with potential AR NTD binding.

bioRxiv · Oct 17, 2022 · PreprintMolecular Biology