NeuroscienceNeuropharmacologyPeer-reviewed
Repeated swim exposure and PKN1a knockout enhance group I mGluR-dependent excitability associated with reduced EAAT3 expression in mouse dentate granule cells
Hiroki Yasuda, Koji Kubouchi, Kenji Hanamura…·Hideyuki Mukai
This study shows that repeated swim exposure and PKN1a knockout increase excitability in mouse dentate granule cells by reducing EAAT3 expression and mGluR activity, while also decreasing anxiety-like behavior.
DOI 10.1016/j.neuropharm.2026.111252