Hideyuki Mukai

This study shows that repeated swim exposure and PKN1a knockout increase excitability in mouse dentate granule cells by reducing EAAT3 expression and mGluR activity, while also decreasing anxiety-like behavior.

The paper demonstrates that baseline-normalized metrics are essential for accurately interpreting fear memory in mice, showing that conventional freezing scores confound locomotor activity.

This study shows that high Na or K concentrations rapidly reduce AGC kinase activation-loop phosphorylation, which recovers when ion concentrations decrease, through an ATP-independent phosphate recycling mechanism.