Polyamine elevation and nitrogen stress are toxic hallmarks of chronic sleep loss in Drosophila melanogaster
Joseph L. Bedont, Anna Kolesnik, Pavel Pivarshev, Dania M. Malik, Cynthia T. Hsu, Aalim M. Weljie, Amita Sehgal
This study identifies polyamine elevation and nitrogen stress as toxic consequences of chronic sleep loss in Drosophila, linking them to metabolic dysfunction and reduced survival.
Current Biology · Mar 24, 2023Peer-reviewedNeuroscience