Ines Serra

This study shows that Purkinje cell intrinsic activity before synaptic maturation is critical for dendrite growth, connectivity, and cerebellar function, with early disruptions causing severe morphological and functional defects.

The paper identifies a genetic overlap between inborn errors of immunity and neurodevelopmental disorders, finding that one-third of IEI-causing genes are also linked to NDDs.

This paper investigates how Tsc1 haploinsufficiency affects cerebellar development in mice, finding dysregulated Pax2 expression and mTOR pathway changes linked to ASD-like phenotypes.

This study investigates neurodevelopmental deficits in activated PI3Kδ syndrome (APDS) using patient assessments and a murine model, showing visuomotor and motor impairments linked to PIK3CD mutations.

This study examines individual differences in eyeblink conditioning performance and brain-wide C-fos expression in male and female mice across strains, finding comparable variability and correlations between locomotion and learning.