Author

Joshua J. White

Baylor College of MedicineORCID 0000-0002-6218-623XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Amanda M BrowniD· 2 shared Roy V. SillitoeiD· 2 shared Tao LiniD· 2 shared Aleksandra BaduraiD· 1 shared Catarina OsórioiD· 1 shared Daniel R. Catt· 1 shared Eleonora RegoloiD· 1 shared Elizabeth P. LackeyiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Amanda M BrownORCID

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3 papers

Recent·Most cited

Purkinje cell intrinsic activity shapes cerebellar development and function

Catarina Osório, Joshua J. White, Paula Torrents-Solé, Jie Yang, Nienke Mandemaker, Federico Olivero, Freya Kirwan, Laura C. Post, Zahra Hemmat, Fred de Winter, Eleonora Regolo, Francesca Romana Fiocchi, Ines Serra, Saffira Tjon, Zeliha Özgür, , Martijn Schonewille

This study shows that Purkinje cell intrinsic activity before synaptic maturation is critical for dendrite growth, connectivity, and cerebellar function, with early disruptions causing severe morphological and functional defects.

Nature Communications · Mar 9, 2026Peer-reviewedNeuroscience

Cerebellar Purkinje cell microcircuits are essential for tremor

Amanda M Brown, Joshua J. White, Meike E. van der Heijden, Tao Lin, Roy V. Sillitoe

This study shows that Purkinje cell activity is essential for tremor, as silencing it blocks tremor in mice and modulating it with deep brain stimulation reduces tremor.

bioRxiv · Sep 15, 2019 · PreprintNeuroscience

Molecular layer interneurons shape the spike activity of cerebellar Purkinje cells

Amanda M Brown, Marife Arancillo, Tao Lin, Daniel R. Catt, Joy Zhou, Elizabeth P. Lackey, Trace L. Stay, Zhongyuan Zuo, Joshua J. White, Roy V. Sillitoe

The paper investigates how inhibitory molecular layer interneurons influence Purkinje cell firing properties in mice by selectively depleting GABAergic neurotransmission from stellate or basket cells.

Scientific Reports · Feb 11, 2019Peer-reviewedNeuroscience