Catarina Osório

This study shows that Purkinje cell intrinsic activity before synaptic maturation is critical for dendrite growth, connectivity, and cerebellar function, with early disruptions causing severe morphological and functional defects.

This paper investigates how Tsc1 haploinsufficiency affects cerebellar development in mice, finding dysregulated Pax2 expression and mTOR pathway changes linked to ASD-like phenotypes.

This study shows TRPC3 is essential for functional heterogeneity in cerebellar Purkinje cells by affecting simple and complex spike activity and behavior related to specific modules.