Aleksandra Badura

The paper examines the relationship between infant muscle tone and cerebellar morphology in adolescence, finding specific cerebellar volume associations but no mediation of autistic traits.

This study shows early cerebellar morphology drives neocortical maturation in a regionally specific manner across humans and mice.

This study shows that Purkinje cell intrinsic activity before synaptic maturation is critical for dendrite growth, connectivity, and cerebellar function, with early disruptions causing severe morphological and functional defects.

This study reviews sex differences in additive genetic effects related to autism, finding inconclusive evidence but suggesting higher polygenic scores in females without intellectual disability.

The paper develops a computational model of olivocerebellar modules to study synaptic plasticity dynamics and shows how IO neuron oscillations and coupling regulate plasticity in Upbound and Downbound micromodules.

The paper identifies a genetic overlap between inborn errors of immunity and neurodevelopmental disorders, finding that one-third of IEI-causing genes are also linked to NDDs.

This study examines cerebellar dentate nucleus neuronal activity during a visual attention task in rhesus macaques, revealing dynamic encoding of visual stimuli and task-related behavior.

The paper uses multi-parametric behavioral assays to capture sex- and environment-dependent behavioral differences in autism mouse models, showing improved classification accuracy compared to classical tests.

This paper investigates how Tsc1 haploinsufficiency affects cerebellar development in mice, finding dysregulated Pax2 expression and mTOR pathway changes linked to ASD-like phenotypes.

This paper introduces an automated method to quantify burying bouts and activity characteristics in the marble burying test using machine learning, revealing differences in behavior across mouse models of neurodevelopmental disorders.

This study investigates neurodevelopmental deficits in activated PI3Kδ syndrome (APDS) using patient assessments and a murine model, showing visuomotor and motor impairments linked to PIK3CD mutations.

This study examines individual differences in eyeblink conditioning performance and brain-wide C-fos expression in male and female mice across strains, finding comparable variability and correlations between locomotion and learning.

This study investigates Purkinje cell activity in the medial and lateral cerebellum of rhesus macaques during antisaccade tasks, revealing distinct roles in volitional eye movement suppression.