In situ structure of a dimeric hibernating ribosome from a eukaryotic intracellular pathogen
Mathew McLaren, Patricia Gil‐Díez, Michail N. Isupov, Rebecca Conners, Lavinia Gambelli, Vicki A. M. Gold, Andreas Walter, Sean R. Connell, Ben Williams, Bertram Daum
The paper investigates hibernating ribosomes in the microsporidian parasite Spraguea lophii using cryoET and cryoEM, revealing a unique dimeric structure and the role of MDF1 in translation inhibition.
bioRxiv · Apr 29, 2022 · PreprintMolecular Biology