Improving Functional Muscle Regeneration in Volumetric Muscle Loss Injuries by Shifting the Balance of Inflammatory and Pro-Resolving Lipid Mediators
Thomas C. Turner, Frank S. Pittman, Hongmanlin Zhang, Lauren A. Hymel, Tianyi Zheng, Monica Behara, Shannon E. Anderson, Julia Andraca Harrer, Kaitlyn A. Link, Mashoor Al Ahammed, Kristal M. Maner-Smith, Xueyun Liu, Xuanzhi Yin, Hong Seo Lim, Matthew R. Spite, , Edward A. Botchwey
This study shows that delivering a stable isomer of Resolvin D1 via a hydrogel improves muscle regeneration and reduces inflammation in volumetric muscle loss injuries.
bioRxiv · Sep 6, 2024 · PreprintBioengineering