Hongmanlin Zhang

This paper introduces Volumetric Scattering Microscopy (VSM), a computational framework for 3D fluorescence imaging in scattering biological media, achieving high-fidelity volumetric reconstruction across various samples.

PAVR enables high-resolution volumetric imaging of cells using a physics-aware framework trained on simulated data, demonstrating applications in tracking subcellular structures and analyzing cardiac cell dynamics.

The paper shows that exogenous sphingomyelinase increases MSC-derived EV yield and alters their cargo, enhancing therapeutic effects in a murine wound model.

This study shows that sphingomyelinase treatment alters lipid and protein metabolites in MSCs, enhancing their immunomodulatory properties similar to cytokine-based priming.

This study identifies an aberrant FAP subpopulation in VML that drives fibrosis and presents potential targets for scarless muscle regeneration.

This study shows that delivering a stable isomer of Resolvin D1 via a hydrogel improves muscle regeneration and reduces inflammation in volumetric muscle loss injuries.