Author

William Austin Wyant

Boston UniversityORCID 0000-0002-2277-1549Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron Richard WaddelliD· 2 shared Kassidy LeibowitziD· 2 shared Marianne CollardiD· 2 shared Nicole GrbiciD· 2 shared Rhoda M. AlaniiD· 2 shared Kihyun ParkiD· 1 shared Philip A. ColeiD· 1 shared Sabah ChoudhuryiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersCancer Biology

Aaron Richard WaddellORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedJul 12, 2024

p300 KAT regulates SOX10 stability and function in human melanoma

Aaron Richard Waddell, Nicole Grbic, Kassidy Leibowitz…·Rhoda M. Alani

This study identifies p300 KAT as a regulator of SOX10 stability and function in melanoma, showing that inhibiting p300 reduces SOX10 levels and melanoma proliferation and invasion.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintFeb 14, 2024

The p300 KAT inhibitor, A-485, inhibits melanogenesis and melanin content in human melanocytes

Nicole Grbic, Aaron Richard Waddell, Kassidy Leibowitz…·Rhoda M. Alani

This study shows that the p300 inhibitor A-485 reduces melanin production in human melanocytes by decreasing MITF and DCT expression.

DOI 10.1101/2024.02.14.580089

humanbulk RNA-seq

𝕏 PostBluesky