Youngchul Kim

This study identifies Y218 phosphorylation in CD28 as critical for IL-2 secretion and antitumor efficacy of CAR-T cells, showing that enhancing ITK recruitment improves therapeutic outcomes.

This study develops a lung cancer prediction model for Korean never-smokers using polygenic risk scores, finding higher odds ratios and improved AUC with PRSs.

PDXGEM builds a gene expression model to predict cancer patient responses to anticancer therapies using data from patient-derived xenograft models.