Erythroferrone Modulates Osteoblast-Osteoclast Crosstalk During Bone Remodeling
Pinanong Na-Phatthalung, Gabrielle van Caloen, Marina Planoutene…·Yelena Z. Ginzburg
This study shows that osteoclast-derived erythroferrone (ERFE) regulates bone mass by modulating osteoblast-osteoclast communication, with ERFE loss in osteoclasts leading to increased osteoclastogenesis and bone loss.