Justine Bruse

This study shows that the constitutive androstane receptor (CAR) protects against MASLD in males through interactions with gut microbiota, but not in females.

This study shows that soluble fiber inulin reduces liver fat and metabolic issues in mice on a Western diet, while insoluble fiber cellulose does not, suggesting inulin's benefits come from its effect on gut microbiota.

This study shows thermoneutral housing worsens MASLD in mice by increasing obesity, inflammation, fibrosis, and impairing BAT activation during β3-adrenergic stimulation.

This study shows that juvenile protein restriction in mice reduces sexual dimorphism by affecting somatic growth, energy metabolism, and hepatic molecular identity, with distinct adaptations in reproductive development.

The paper shows that repeated fasting events sensitize enhancers and gene expression to enhance ketogenesis in mice.