Author

Shiun Chang

Moffitt Cancer CenterORCID 0000-0002-2320-727XUnclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ahmed RamadaniD· 1 shared Daniel Abate‐DagaiD· 1 shared Daniel AntfolkiD· 1 shared David González-PéreziD· 1 shared David H. PereziD· 1 shared Elliot MedinaiD· 1 shared Paulo C. Rodrı́gueziD· 1 shared Vincent C. LucaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperSynthetic Biology

Ahmed RamadanORCID

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1 paper

Recent·Most cited

Synthetic BiologyNature Chemical BiologyPeer-reviewedSep 24, 2025

Engineering synthetic agonists for targeted activation of Notch signaling

David H. Perez, Daniel Antfolk, Shiun Chang…·Vincent C. Luca

This paper develops synthetic Notch agonists (SNAGs) that activate Notch signaling by pulling on mechanosensitive receptors, demonstrating their effectiveness in targeting multiple biomarkers.

5 citations

humanexperimental assay

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