Systems BiologybioRxivPreprint
Asymmetric co-substrate usage at a metabolic branch point as a minimal network motif that can drive overflow metabolism
Robert West, Sonal, Tailise Carolina de Souza‐Guerreiro…·Orkun S. Soyer
The paper identifies asymmetric co-substrate usage at a metabolic branch point as a mechanism that enables flux switching and drives overflow metabolism, validated through modeling and experimental data in yeast.
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