Author

Hyeonju Kim

University of Tennessee Health Science CenterORCID 0000-0002-2368-4850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Śaunak SeniD· 3 shared Gregory FarageiD· 2 shared Amin HaghaniiD· 1 shared Chelsea TrotteriD· 1 shared Flavia VillaniiD· 1 shared John K. Mckay· 1 shared John T. LovelliD· 1 shared Karl W. BromaniD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersGenetics

Śaunak SenORCID

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3 papers

Recent·Most cited

Pleiotropic Influence of DNA Methylation QTLs on physiological and aging traits

Khyobeni Mozhui, Hyeonju Kim, Flavia Villani, Amin Haghani, Śaunak Sen, Steve Horvath

The paper identifies a regulatory hotspot, meQTL.5a, that influences DNA methylation, gene expression, and aging traits in mice through genetic and age-related factors.

bioRxiv · Apr 12, 2023 · PreprintGenomics

Speeding up eQTL scans in the BXD population using GPUs

Chelsea Trotter, Hyeonju Kim, Gregory Farage, Pjotr Prins, Robert W. Williams, Karl W. Broman, Śaunak Sen

The paper develops GPU-accelerated algorithms for fast eQTL scans in BXD mice, reducing runtime to seconds for large transcriptome datasets.

G3 Genes Genomes Genetics · Aug 16, 2021Peer-reviewedGenetics

Flexible multivariate linear mixed models for structured multiple traits

Hyeonju Kim, Gregory Farage, John T. Lovell, John K. Mckay, Thomas E. Juenger, Śaunak Sen

This paper introduces FlxQTL, a flexible multivariate linear mixed model for genetic mapping of multiple correlated traits, adjusting for relatedness and modeling multiple environments or timepoints.

bioRxiv · Mar 27, 2020 · PreprintGenetics