Kelly D. Smith

This study uses human precision cut kidney slices to analyze gene expression responses to culture conditions and IFNγ stimulation, showing reproducible APOL1 expression changes.

This paper designs multivalent RBD nanoparticle vaccines that overcome immune imprinting and provide broad protection against SARS-CoV-2 variants and sarbecoviruses.

This study evaluates the rigor and reproducibility of digital spatial profiling in clinically sourced human tissues, finding it to be highly reliable.

The paper uses genome-edited human kidney organoids and single-cell transcriptomics to study APOL1 risk variants' effects on kidney disease mechanisms.