Author
Northwestern UniversityORCID 0000-0003-2875-5184Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Andrew O. Kearney, Johnson Y. Yang, Esther Liu…·Jennie J. Lin
This study shows that APOL1 G1 and G2 risk alleles affect diet-induced obesity severity differently in male and female transgenic mice.
Esther Liu, Matthew Wright, Andrew O. Kearney…·Jennie J. Lin
This study shows G1 and G2 APOL1 variants increase macrophage inflammation and lipid accumulation via the polyamine pathway, which can be inhibited by DFMO.
Esther Liu, Behram Radmanesh, Byung Ha Chung…·Jennie J. Lin
The paper uses genome-edited human kidney organoids and single-cell transcriptomics to study APOL1 risk variants' effects on kidney disease mechanisms.