Author

Sidong Liu

Macquarie UniversityORCID 0000-0002-2371-0713Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Organism:human· 2 Assay:imaging· 2 Approach:contrastive learning· 1 Approach:deep learning· 1 Approach:diffusion model· 1 Approach:experimental assay· 1 Research Focus:imputation· 1

Frequent Co-Authors

James S. WilmottiD· 2 shared Nurudeen Adedayo AdegokeiD· 2 shared Priyanka RanaiD· 2 shared Tuba Nur GideiD· 2 shared Xingnan Li· 2 shared Yizhe MaoiD· 2 shared Albert J. VilellaiD· 1 shared Alexandra Palmer· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

James S. WilmottORCID

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Author profile →

3 papers

Recent·Most cited

OS2CR-Diff: A Self-Refining Diffusion Framework for CD8 Imputation from One-Step Inference to Conditional Representation

Xingnan Li, Priyanka Rana, Tuba Nur Gide, Nurudeen Adedayo Adegoke, Yizhe Mao, James S. Wilmott, Sidong Liu

OS2CR-Diff improves CD8 biomarker imputation in mIF images by using a self-refining diffusion model with multiple conditional inputs and a feature fusion module.

IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · Dec 15, 2025Peer-reviewedBioinformatics

AdSI-MIMO: Adaptive stain imputation with multi-input and multi-output learning for multiplex immunofluorescence imaging

Xingnan Li, Priyanka Rana, Tuba Nur Gide, Nurudeen Adedayo Adegoke, Yizhe Mao, Shlomo Berkovsky, Enrico W Coiera, James S. Wilmott, Sidong Liu

AdSI-MIMO improves stain imputation for multiplex immunofluorescence images by generating multiple biomarker outputs from varied input combinations, achieving better performance for CD8 and PD-L1 imputation.

bioRxiv · Jun 27, 2025 · PreprintBioinformatics

Accurate simultaneous sequencing of genetic and epigenetic bases in DNA

Jens Füllgrabe, Walraj S. Gosal, Páidí Creed, Sidong Liu, Casper K. Lumby, David J. Morley, Tobias W. B. Ost, Albert J. Vilella, Shirong Yu, Helen Bignell, Philippa Burns, Tom Charlesworth, Beiyuan Fu, Howerd Fordham, Nicholas J. Harding, , Shankar Balasubramanian

This paper introduces a method to simultaneously sequence genetic and epigenetic bases in DNA with single-base resolution, demonstrating accuracy and versatility in human genomic and cell-free DNA samples.

Nature Biotechnology · Feb 6, 2023Peer-reviewedGenomics