Author

James S. Wilmott

Melanoma Institute AustraliaORCID 0000-0002-6750-5244Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:imaging· 2 Approach:statistical model· 2 Approach:contrastive learning· 1 Approach:deep learning· 1

Frequent Co-Authors

Georgina Venetia LongiD· 2 shared Matthew J. WongchenkoiD· 2 shared Nurudeen Adedayo AdegokeiD· 2 shared Priyanka RanaiD· 2 shared Richard A. ScolyeriD· 2 shared Sidong LiuiD· 2 shared Tuba Nur GideiD· 2 shared Xingnan Li· 2 shared

Activity by Year

2018-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Georgina Venetia LongORCID

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Author profile →

5 papers

Recent·Most cited

OS2CR-Diff: A Self-Refining Diffusion Framework for CD8 Imputation from One-Step Inference to Conditional Representation

Xingnan Li, Priyanka Rana, Tuba Nur Gide, Nurudeen Adedayo Adegoke, Yizhe Mao, James S. Wilmott, Sidong Liu

OS2CR-Diff improves CD8 biomarker imputation in mIF images by using a self-refining diffusion model with multiple conditional inputs and a feature fusion module.

IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · Dec 15, 2025Peer-reviewedBioinformatics

AdSI-MIMO: Adaptive stain imputation with multi-input and multi-output learning for multiplex immunofluorescence imaging

Xingnan Li, Priyanka Rana, Tuba Nur Gide, Nurudeen Adedayo Adegoke, Yizhe Mao, Shlomo Berkovsky, Enrico W Coiera, James S. Wilmott, Sidong Liu

AdSI-MIMO improves stain imputation for multiplex immunofluorescence images by generating multiple biomarker outputs from varied input combinations, achieving better performance for CD8 and PD-L1 imputation.

bioRxiv · Jun 27, 2025 · PreprintBioinformatics

Tissue-wide profiling of human lungs reveals spatial sequestration of macrophages in tuberculosis

Wei Lie Xiao, Andrew J. Sawyer, Siwei Mo, Xinyu Bai, Qinzhu Yang, Yi Gao, Timothy Fielder, Yue Zhang, Youchao Dai, Qianting Yang, Yi Cai, Guanggui Ding, Guofang Deng, Liang Fu, Camelia Y. J. Quek, , Xinchun Chen

Xiao et al. reveal spatial segregation of immune cells in TB-lung tissue and link the microenvironmental dynamics to disease states of tuberculosis.

bioRxiv · Apr 11, 2025 · PreprintImmunology

Tumour gene expression signature in primary melanoma predicts long-term outcomes: A prospective multicentre study

Manik Garg, Dominique‐Laurent Couturier, Jérémie Nsengimana, Nuno A. Fonseca, Matthew J. Wongchenko, Yibing Yan, Martin Lauss, Goran B Jönsson, Julia Newton‐Bishop, Christine Parkinson, Mark Ross Middleton, David Timothy Bishop, Sarah McDonald, Nikki Stefanos, John A. Tadross, , Roy Rabbie

This paper develops a gene expression signature, Cam_121, to predict long-term outcomes in primary melanoma patients, showing improved accuracy compared to clinical and existing prognostic models.

Nature Communications · Feb 18, 2021Peer-reviewedBioinformatics

bcGST - an interactive bias-correction method to identify over-represented gene-sets in boutique arrays

Kevin Y. X. Wang, Alexander Maxwell Menzies, Inês Pires da Silva, James S. Wilmott, Yibing Yan, Matthew J. Wongchenko, Richard F. Kefford, Richard A. Scolyer, Georgina Venetia Long, Garth Tarr, Samuel Mueller, Jean Yee Hwa Yang

bcGST corrects bias in gene set tests for boutique arrays by adjusting Fisher's Exact Test to account for incomplete genome coverage.

Bioinformatics · Sep 11, 2018Peer-reviewedBioinformatics