Neonatal Platelets Differentiate Monocytes to a Myeloid Derived Suppressor Cell Phenotype
Preeti Maurya, Daniel P. O’Reilly, Zachary T. Hilt…·Craig N. Morrell
This study shows neonatal platelets induce monocytes to a Myeloid Derived Suppressor Cell phenotype, limiting T-cell activation, which may explain adverse outcomes of platelet transfusions in neonates.