Zachary T. Hilt

This study shows neonatal platelets induce monocytes to a Myeloid Derived Suppressor Cell phenotype, limiting T-cell activation, which may explain adverse outcomes of platelet transfusions in neonates.

This study identifies the L260F mutation in NSP6 as enhancing RNA replication and pathogenesis in recent SARS-CoV-2 variants, independent of Spike function.

A single amino acid substitution in CD28 enhances signaling, leading to increased CD8 activation and Tpex generation during viral infection, while accelerating exhaustion in chronic infection.

This study shows that recent thymic emigrants are preferentially recruited into the memory pool during persistent CMV infection, while mature CD8+ T cells contribute little.