Author

Jesse G. Kennedy

South Australian Health and Medical Research InstituteORCID 0000-0002-2375-7538Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Ashleigh GeigeriD· 1 shared Caleb LushingtoniD· 1 shared Chandran PfitzneriD· 1 shared Fatwa AdikusumaiD· 1 shared G.I. GodahewaiD· 1 shared Jayshen ArudkumariD· 1 shared Lachlan G. StakeriD· 1 shared Louise J. RobertsoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Ashleigh GeigerORCID

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1 paper

Recent·Most cited

Enhancing gRNA Transcript levels by Reducing the Scaffold Poly-T Tract for Optimal SpCas9- and SaCas9-mediated Gene Editing

Yu Chinn Joshua Chey, Luke Gierus, Caleb Lushington, Jayshen Arudkumar, Ashleigh Geiger, Lachlan G. Staker, Louise J. Robertson, Chandran Pfitzner, Jesse G. Kennedy, Ryan H. B. Lee, G.I. Godahewa, Paul Quinton Thomas, Fatwa Adikusuma

This study shows that shortening the 4T poly-T tract in gRNA scaffolds improves transcript levels and editing efficiency, especially under low vector conditions, for both SpCas9 and SaCas9.

BMC Genomics · Feb 12, 2025Peer-reviewedMolecular Biology