Yin Liu

The paper identifies Igf2 as an injury-activated mitogen for neuroendocrine stem cells and shows its role in cancer initiation through receptor activation and Rb repression.

The paper uses single-cell RNA sequencing to identify and characterize neuropeptide and peptide hormone genes in pulmonary neuroendocrine cells from mice and humans, revealing their diverse signaling roles and potential endocrine functions.

Portal integrates large-scale single-cell datasets efficiently and accurately by preserving biological variation across samples, platforms, and species.

The paper presents a transcriptomic atlas of mouse lung interoceptors, identifying 10 molecular subtypes with distinct functional roles in breathing control.