Xue Wang

Identification of a basal stem cell subpopulation in the prostate via functional, lineage tracing and single-cell RNA-seq analyses

The paper identifies a basal stem cell subpopulation in the prostate using lineage tracing, functional analysis, and single-cell RNA-seq, showing Zeb1+ cells are multipotent prostate basal stem cells.

E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo

This study shows that E-cadherin connects cell polarity and spindle orientation in prostate epithelial cells, preventing carcinogenesis.