Metabolic effects and biotransformation of perfluorohexyloctane (F6H8) in human hepatocytes
Andi Alijagić, Jade Chaker, João Marcos G. Barbosa, Daniel Duberg, Victor Castro‐Alves, Alex M. Dickens, Matej Orešič, Tuulia Hyötyläinen
This study examines the metabolic effects and biotransformation of F6H8 in human hepatocytes, revealing concentration-dependent metabolic alterations and the formation of a PFAS-like biotransformation product.
bioRxiv · Oct 24, 2025 · PreprintPharmacology & Toxicology