GeneticsOpen BiologyPeer-reviewed
REV1 inhibition enhances trinucleotide repeat mutagenesis
Ava Siegel, Daniel Almstead, Naveen Kothandaraman…·Nimrat Chatterjee
This study shows that inhibiting REV1, a TLS polymerase, increases trinucleotide repeat instability in human cells, suggesting REV1 protects against TNR mutagenesis.
2 citations