Author

Naveen Kothandaraman

University of VermontPrimary ORCID profile (0009-0007-4631-7643 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Naveen KothandaramaniD1 paper · University of Vermont;

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Andrew CromptoniD· 2 shared Dmitry M. KorzhneviD· 2 shared Matthew Kyle HaddeniD· 2 shared Nimrat ChatterjeeiD· 2 shared Aarzoo Grover· 1 shared Ava SiegeliD· 1 shared Daniel AlmsteadiD· 1 shared Erica N. LamkiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Andrew CromptonORCID

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2 papers

Recent·Most cited

Targeting REV7 exposes a mitotic vulnerability in colorectal cancer cells

Madison Guyette, Sombodhi Bhattacharya, Naveen Kothandaraman, Vihit Gupta, Andrew Crompton, Katherine Boyle, Noah J. Harrahill, Jon Ramsey, Dmitry M. Korzhnev, Matthew Kyle Hadden, Nimrat Chatterjee

This study shows that targeting REV7 with C10 sensitizes colorectal cancer cells to microtubule disruption, revealing a mitotic vulnerability.

bioRxiv · Sep 30, 2026 · PreprintCancer Biology

REV1 inhibition enhances trinucleotide repeat mutagenesis

Ava Siegel, Daniel Almstead, Naveen Kothandaraman, Jessica Reich, Erica N. Lamkin, Joshua Victor, Aarzoo Grover, Kanayo Ikeh, Hannah Koval, Andrew Crompton, Hongjun Jang, Hyejin Lee, Roxana del Río, Dmitry M. Korzhnev, Matthew Kyle Hadden, , Nimrat Chatterjee

This study shows that inhibiting REV1, a TLS polymerase, increases trinucleotide repeat instability in human cells, suggesting REV1 protects against TNR mutagenesis.

Open Biology · Dec 1, 2025Peer-reviewedGenetics