Author
Duke UniversityORCID 0000-0001-9312-0084Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Ssu-Yu Chen, You Zou, Jianli Wu…·Jen‐Tsan Chi
This study identifies RBM39 as a noncovalent target of the KRAS G12C inhibitor divarasib and reveals an RBM39-INSR signaling axis that influences cytotoxicity.
Ava Siegel, Daniel Almstead, Naveen Kothandaraman…·Nimrat Chatterjee
This study shows that inhibiting REV1, a TLS polymerase, increases trinucleotide repeat instability in human cells, suggesting REV1 protects against TNR mutagenesis.
C Williams, Xin Li, Hongjun Jang…·Pei Zhou
The paper shows that AR inhibition in prostate cancer causes DNA replication stress, which can be exploited by combining with a TLS inhibitor to enhance treatment efficacy.