Korbinian Liebl

CRANBERRY: A Coarse-grained RNA Model with Sugar Puckering and Noncanonical Base Pairing

CRANBERRY is a coarse-grained RNA model that includes sugar puckering and noncanonical base pairing, achieving performance comparable to all-atom models in structural predictions and experimental agreement.

Mechanisms of MCM2-7 helicase activation and initial DNA melting at near base-pair resolution

The paper identifies a DNA-bound intermediate during MCM2-7 helicase activation and shows how DNA unwinding is coupled to helicase complex disassembly and DNA exit.

Membrane Remodeling by the Collective Action of Caveolin-1

This study develops a coarse-grained model to investigate how caveolin-1 proteins drive membrane curvature through collective interactions.

Deciphering DNA's sequence-dependent structure and deformability with normalizing flows

This paper introduces an AI-based method using normalizing flows to accurately model DNA sequence-dependent structure and deformability, capturing complex correlations between internal coordinates.

Lipid Organization by the Caveolin-1 Complex

This study uses molecular dynamics simulations to show how the CAV1-8S complex bends membranes and extracts cholesterol, revealing limitations of the Martini v2 forcefield.