Alain Garcia De Las Bayonas

An adhesion GPCR regulates cell adhesion and mating in the closest living relatives of metazoans

This study identifies Cupidon, an adhesion GPCR in Salpingoeca rosetta, which regulates cell adhesion and mating by modulating proteolytic processing and localization during nutrient conditions.

G protein-coupled receptor diversity and evolution in the closest living relatives of Metazoa

The paper catalogs GPCRs, G proteins, and regulators in choanoflagellates, revealing expanded diversity and conserved families, with implications for metazoan GPCR evolution.

Distinct RhoGEFs activate apical and junctional actomyosin contractility under control of G proteins during epithelial morphogenesis

The paper identifies distinct RhoGEFs that regulate apical and junctional actomyosin contractility in Drosophila ectoderm through G protein signaling during epithelial morphogenesis.