Developmental BiologyDevelopmental CellPeer-reviewed
Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry
Jules Lavalou, Qiyan Mao, Stefan Harmansa…·Thomas Lecuit
The paper shows that Toll-8 and Cirl GPCRs form an asymmetric complex to polarize Myosin-II, driving planar cell intercalations during Drosophila embryonic axis extension.
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