Author
Institute of Genomics and Integrative BiologyORCID 0000-0002-2419-2882Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Sangita Chowdhury Paul, Juhi Bhardwaj, Srishti Sharma…·Balachandran Krishnamma Binukumar
This study shows that Lepr haploinsufficiency accelerates Alzheimer-like neurodegeneration in mice through CDK5 hyperactivation and identifies pathogenic LEPR variants in humans.
Sangita Chowdhury Paul, Chandran Remya, Kalarickal Vijayan Dileep…·Balachandran Krishnamma Binukumar
This study identifies novel Cdk5 inhibitors that improve T2D symptoms and cognitive function in a mouse model.
Bhaskar Jyoti Saikia, Utkarsh Gaharwar, Mukta Poojary…·Balachandran Krishnamma Binukumar
The paper curates and annotates 5118 pathogenic/likely pathogenic variants from 118 movement disorder-associated genes using ACMG & AMP guidelines, creating a comprehensive online compendium called DystoGen.
Sangita Chowdhury Paul, Saman Fatihi, Srishti Sharma…·Balachandran Krishnamma Binukumar
The paper investigates how CDK5 phosphorylates cPLA2 in Parkinson's Disease, leading to neuroinflammation and identifies potential therapeutic targets.