Author

Saman Fatihi

Institute of Genomics and Integrative BiologyORCID 0000-0002-9781-9009Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:variant calling· 2 Organism:virus· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Lipi ThukraliD· 4 shared Ankit Kumar PathakiD· 2 shared Mitali MukerjiiD· 2 shared Aayushi Singh· 1 shared Abhinav K. JainiD· 1 shared Amol M. KanampalliwariD· 1 shared Anirban BanerjeeiD· 1 shared Arup GhoshiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersBiophysics

Lipi ThukralORCID

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4 papers

Recent·Most cited

BiophysicsEMBO ReportsPeer-reviewedSep 25, 2026

LC3 forms functional nanocluster on autophagosome

Saman Fatihi, Deepak M Khushalani, Joydipta Kar…·Lipi Thukral

The paper shows LC3B forms nanoclusters on autophagosomes via specific lipid interactions and a unique binding pocket, impacting autophagosome motility.

1 citationtop 5%

mechanistic / dynamical modelmicroscopy & imaging analysis

𝕏 PostBluesky

GenomicsNucleic Acids ResearchPeer-reviewedJan 13, 2022

Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes

Ankit Kumar Pathak, Gyan Prakash Mishra, Bharathram Uppili…·Mitali Mukerji

The paper analyzes intra-host Single Nucleotide Variations (iSNVs) in SARS-CoV-2 genomes across multiple time points and regions, finding that many iSNVs later become population-level variants and some may contribute to immune escape.

28 citations

viruswhole-genome sequencing

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 5, 2021

CDK5 mediated phosphorylation of cytosolic phospholipase A2 regulates its activity and neuroinflammation in Parkinsons Disease

Sangita Chowdhury Paul, Saman Fatihi, Srishti Sharma…·Balachandran Krishnamma Binukumar

The paper investigates how CDK5 phosphorylates cPLA2 in Parkinson's Disease, leading to neuroinflammation and identifies potential therapeutic targets.

DOI 10.1101/2021.11.05.467380

humanstatistical model

𝕏 PostBluesky

BioinformaticsCurrent Research in Structural BiologyPeer-reviewedJan 1, 2021

A rigorous framework for detecting SARS-CoV-2 spike protein mutational ensemble from genomic and structural features

Saman Fatihi, Surabhi Rathore, Ankit Kumar Pathak…·Lipi Thukral

The paper identifies mutational patterns in SARS-CoV-2 spike protein using genomic and structural data, finding structural changes that may affect vaccine efficacy.

20 citations

viruswhole-genome sequencing

𝕏 PostBluesky