Author

Eva M. Hoekstra

Leiden University Medical CenterORCID 0000-0002-2437-6016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Corrie M. WorteliD· 1 shared Cynthia M. FehresiD· 1 shared E. W. Nivine LevarhtiD· 1 shared Hans Ulrich SchereriD· 1 shared JK de Vries-BouwstraiD· 1 shared Nynke H. DekkeriD· 1 shared René E.M. ToesiD· 1 shared Sam NeppelenbroekiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Corrie M. WortelORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Clonal autoantibodies identify microbial antigen as trigger of autoreactive B cells in systemic sclerosis

Sam Neppelenbroek, Sophie I E Liem, Theo van Laar, Eva M. Hoekstra, Corrie M. Wortel, E. W. Nivine Levarht, Cynthia M. Fehres, Nynke H. Dekker, JK de Vries-Bouwstra, René E.M. Toes, Hans Ulrich Scherer

The paper identifies microbial antigen, specifically fungal topoisomerase 1, as a trigger for autoreactive B cells in systemic sclerosis by showing cross-reactivity between human and microbial TOP1.

bioRxiv · Mar 19, 2026 · PreprintImmunology