Regulation of NTRK2 alternative splicing by PRPF40B controls neural differentiation and synaptic plasticity
María Duarte-Ruiz, Adela Moreno-Castillo, Younes El Yousfi, Cristina Moreno‐Castro, Noelia Martínez-Martínez, Sandra Jiménez-Lozano, Marion Kennel, Candela Ruiz-Rodríguez, Alonso Rodríguez-Caparrós, Jennifer López-Ros, Pierre de la Grange, Cristina Hernández-Munaín, Carlos Suñé
This study identifies PRPF40B as a regulator of NTRK2 alternative splicing, influencing TRKB isoform production and impacting neuronal differentiation and synaptic plasticity.
Cell Death and Disease · Dec 8, 2025Peer-reviewedCell Biology