Carlos Suñé

The paper shows a Tcra enhancer can regulate a distal gene in a different TAD during T-cell development, challenging the idea that TAD boundaries block enhancer-promoter interactions.

This study identifies PRPF40B as a regulator of NTRK2 alternative splicing, influencing TRKB isoform production and impacting neuronal differentiation and synaptic plasticity.

This study shows that human prefoldin affects co-transcriptional pre-mRNA splicing by modulating RNA polymerase II phosphorylation and splicing factor recruitment.